11 days in Rome & Florence Itinerary

Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.

Museum-lovers will get to explore Museo Storico Piana delle Orme and Castello Odescalchi. Step off the beaten path and head to Museo Nazionale Tarquiniense and Chiesa di San Pietro. Change things up with these side-trips from Rome: Ente Parco Naturale Regionale dei Monti Lucretili (in Palombara Sabina), Il Negozietto (in Orvieto) and Lagustelli di Percile (in Percile). There's much more to do: contemplate the long history of Piazza del Duomo, wander the streets of Quartiere San Pellegrino, admire the landmark architecture of Rocca dei Papi, and get curious at Museo Geologico e delle Frane.

For other places to visit, reviews, traveler tips, and more tourist information, you can read our Rome trip itinerary planning site .

If you are flying in from United States, the closest major airports are Leonardo da Vinci–Fiumicino Airport and Ciampino–G. B. Pastine International Airport. In April in Rome, expect temperatures between 69°F during the day and 49°F at night. Wrap up your sightseeing on the 23rd (Tue) to allow time to take a train to Florence.

Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.

Your day-by-day itinerary now includes Corridoio Vasariano as well as Museum of Opera of Saint Maria of Fiore. Kick off your visit on the 24th (Wed): admire the masterpieces at Museum of Opera of Saint Maria of Fiore, learn about winemaking at Enoteca Falorni, then learn about winemaking at Montefioralle Winery, and finally get into the urban bustle at Comune Di Certaldo. Get ready for a full day of sightseeing on the next day: examine the collection at Piccolo museo del diario and then contemplate in the serene atmosphere at La Verna - Franciscan Sanctuary.

To find photos, other places to visit, more things to do, and more tourist information, read our Florence online trip itinerary builder .

You can take a train from Rome to Florence in 2 hours. Other options are to drive; or fly. April in Florence sees daily highs of 67°F and lows of 50°F at night. Wrap up your sightseeing by early afternoon on the 26th (Fri) to allow time for the train ride back home.