11 days in Rome & Florence Itinerary

Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.

Get some historical perspective at Castello Orsini-Odescalchi and Palazzo dei Papi. Get a sense of the local culture at Viterbo Historic Centre and Piazza del Duomo. Venture out of the city with trips to Museo Nazionale Tarquiniense (in Tarquinia), Chiesa di San Pietro (in Tuscania) and Ente Parco Naturale Regionale dei Monti Lucretili (in Palombara Sabina). And it doesn't end there: get to know the fascinating history of Necropoli della Banditaccia, look for gifts at Il Negozietto, get engrossed in the history at Museo Storico Piana delle Orme, and see the interesting displays at Museo Storico dell'Aeronautica Militare.

For where to stay, photos, traveler tips, and other tourist information, go to the Rome vacation planning site.

If you are flying in from United States, the closest major aiports are Leonardo da Vinci–Fiumicino Airport, Ciampino–G. B. Pastine International Airport and Perugia San Francesco d'Assisi – Umbria International Airport. Expect a daytime high around 69°F in April, and nighttime lows around 49°F. Finish your sightseeing early on the 23rd (Tue) so you can take a train to Florence.

Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.

Your day by day itinerary now includes Corridoio Vasariano as well as Museum of Opera of Saint Maria of Fiore. Kick off your visit on the 24th (Wed): take an in-depth tour of Museum of Opera of Saint Maria of Fiore, then do a tasting at Enoteca Falorni, then do a tasting at Montefioralle Winery, and finally take a stroll around Comune Di Certaldo. Keep things going the next day: examine the collection at Piccolo museo del diario and then contemplate in the serene atmosphere at La Verna - Franciscan Sanctuary.

To find more things to do, maps, and tourist information, read our Florence holiday planner.

You can take a train from Rome to Florence in 2.5 hours. Alternatively, you can fly; or drive. In April, daytime highs in Florence are 67°F, while nighttime lows are 50°F. On the 26th (Fri), wrap the sightseeing up by early afternoon so you can take a train back home.